Finding out you’re a werewolf would be a pain in the ass for anyone trying to live a normal life in a modern American city – especially if you’re a struggling vet whose patients now smell like dinner. For a grieving young widow who can barely face her normal life’s problems, transforming into a werewolf just makes things go from bad to worse.
We have at least one vote for working "nearly eats a kitten" in there somehow.
Whether important to the pitch or not, I have also settled (for now) on these other things:
She has just moved to Seattle and is trying to start a new life there.
She was raised on a rural family compound by one of those crazy religious families with a million kids.